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ED Combo Pack

Erectile dysfunction (ED) occurs when a man is unable to gain or maintain an erection sufficiently for penetrative sex. As certain treatments can suit some men better than others, you can now order an ED Combo Pack containing three popular erectile dysfunction medicines.

  • How our service works
    • 1
      Complete your online consultation
    • 2
      Clinicians assess your suitability for your preferred treatment
    • 3
      Click and collect at a LloydsPharmacy, including selected Sainsbury’s stores
    Find out more

    4x Cialis, 4x Sildenafil and 4x Spedra

    ED combo-pack

    Key Features
    • Spedra takes effect within 15 minutes for some men
    • Sildenafil is effective within one hour and can last up to five hours
    • Cialis is fast-acting and lasts longer than other ED treatments
    The ED Combo Pack containing Cialis, Sildenafil and Spedra is a helpful way to judge which medicines works best for you.
    Dr Clyde Mackey

    Key Information

    The medicines

    Cialis, Sildenafil and Spedra

    How to take them

    Cialis - one tablet at least 30 minutes before sex

    Sildenafil - one tablet one hour before sex 

    Spedra - one tablet 15-30 minutes before sex  

    Never take more than one tablet within a 24 hour period.  Avoid taking any of the medicines with more than one or two units of alcohol as this can limit its effectiveness.  Grapefruit juice should be avoided within 24 hours prior to taking Spedra. Full usage instructions will be provided with the prescription.  

    How quickly they work                                                

    Cialis – works within 30 minutes, positive effects can last up to 36 hours

    Sildenafil – works within one hour, positive effects lasts from four to five hours

    Spedra – works within 30 minutes, positive effects can last up to four – five hours                                                 

    How they workThese medications each work by increasing blood flow to the erectile tissue of the penis.  The medicines do not have an effect on your sexual desire, but will improve your erection if you are sexually aroused.
    EffectivenessThe majority of men will notice a firmer and longer lasting erection. If the medications are ineffective, contact us or your GP for further advice.
    Side effectsSide effects are uncommon but can include nausea, vomiting, diarrhoea and an allergic rash. Other side effects include facial flushing, headache, light-heartedness, a stuffy nose, blurred vision, pounding heartbeat and indigestion.
    Nitrates and erectile dysfunction medicinesOur GPs will not be able to prescribe you an erectile dysfunction medicine if you are taking nicorandil or nitrates such as GTN spray or isosorbide mononitrate tablets to treat angina.
    Alpha-blockers and ViagraIf you are taking alpha-blockers, our GPs will not be able to prescribe this starter pack as you cannot take one of the medicines, Cialis, with alpha-blockers. Instead, our doctors may be able to prescribe you Viagra, Spedra or Levitra which are both safe to take six hours after taking alpha-blockers.
    PackagingAll packaging is discreet. You can tell that the delivery has come from LloydsPharmacy, but you can't tell what's inside.

    Taking Cialis, Sildenafil and Spedra

    About Cialis (tadalafil)

    • Cialis should be taken 30 minutes before sex and can remain effective for up to 36 hours
    • Unaffected by food consumption

    Cialis is one of the fastest-acting ED medications and can remain effective for up to 36 hours. It is currently the longest-lasting erectile dysfunction medicine on the market.

    Generally speaking, you can take other medicines with Cialis, however, it interacts badly with certain medicines such as nicorandil and those containing nitrates. Cialis also interacts with alpha blockers e.g. Tamsulosin or Doxazosin. It is important that you tell us about all the medicines you are currently taking so that Cialis can be prescribed safely.

    About Sildenafil (Sildenafil citrate)

    • Sildenafil contains the same active ingredient as Viagra
    • Cheaper than Viagra but works in the same way

    Sildenafil can be effective within an hour of being taken and will last four to five hours. However, the speed and effectiveness of Sildenafil does depend on food and alcohol intake. For best results, you should take Sildenafil without food (or with a low-fat meal) and avoid alcohol consumption. Sildenafil is effective within one hour and can last up to five hours.

    About Spedra (Avanafil)

    • Spedra is fast-acting and can be effective for around four to six hours
    • Gives a firmer and longer-lasting erection when aroused

    Spedra is a targeted medicine and should take effect within 15 to 30 minutes for most men, making it one of the fastest-acting ED medicines on the market.

    Does Cialis, Sildenafil and Spedra treat the underlying causes of erectile dysfunction?

    No. ED medicines do not treat the underlying physical causes of erectile dysfunction such as diabetes, prostate problems or high blood pressure. In addition this medication will not cure psychological issues such as anxiety or having low self-esteem; taking ED medications may boost self-esteem and confidence which can reduce the chances of anxiety-induced erectile dysfunction.

    You should consult your GP for diagnosis of any underlying health conditions.

    Alternative Treatments

    Psychological Therapy

    Some men may want to try counselling to treat psychological causes of erectile dysfunction. Some sexual health clinics (also known as GUM clinics) offer this service if you are interested in counselling. 

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