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Cialis - Erectile dysfunction treatments
  • Can be taken with food
  • Works in 30 mins, lasts up to 36 hours
  • Works for 80% of men

Cialis tablets

Cialis is a reliable, branded ED treatment that lasts up to 36 hours.

Cialis - Erectile dysfunction treatments
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Alternative treatment: Tadalafil

  • Can be taken with food
  • Works in 30 mins, lasts up to 36 hours
  • Works for 80% of men
On this page

    What is Cialis?

    On this page
    1. How does Cialis work?
    2. How long does Cialis take to work?
    3. How long do the effects last?
    4. How effective is Cialis for men?
    5. Who can take Cialis tablets?
    6. How to take Cialis tablets
    7. Can I take Cialis daily?
    8. Are Cialis and Cialis Daily interchangeable?
    9. Cialis dosages
    10. Cialis side effects
    11. Long-term side effects of taking Cialis

    Cialis is a treatment for erectile dysfunction. It contains the active ingredient tadalafil, which belongs to a group of medicines called phosphodiesterase type 5 inhibitors.

    Cialis tablets can work in 30 minutes and because the medicine lasts up to 36 hours, it’s often known as the ‘weekend pill.’ Cialis is effective for 8 out of 10 men experiencing ED.

    There are two different strengths available: 10mg and 20mg.

    This is a standard treatment you take as needed before sex. The Cialis pill lasts up to 36 hours, giving you flexibility and allowing for spontaneity. Other Cialis options include:

    Cialis Daily

    Cialis 2.5mg and Cialis 5mg tablets are lower-dose options you take every day, enabling spontaneous erections whenever you want them. It's ideal if you have sex at least twice weekly and no need to plan ahead.

    Cialis Together

    An over-the-counter treatment for men aged 18 and over. It works within 30 minutes and lasts up to 36 hours, but only when you're sexually stimulated. You can buy Cialis Together online without a prescription.

    How does Cialis work?

    When you're sexually aroused, Cialis helps the blood vessels in your penis to relax, allowing better blood flow. This makes it easier to get and maintain a firmer erection.

    It’s important to understand that Cialis enhances what your body already does naturally rather than replacing it. The medicine supports your body's natural response to sexual stimulation. So it won't work without arousal and it doesn't affect your sexual desire. You'll still need to be turned on for Cialis to be effective, just as you would naturally.

    The effects of Cialis can last up to 36 hours after taking the tablet, giving you a longer window of opportunity.

    “It’s important to assess your lifestyle and any psychological issues before presuming there is something physically wrong. Seeking medication for ED and performance issues but not addressing the initial cause will only prolong the issue.” - Dr Neel Patel  

    How long does Cialis take to work?

    Once taken, Cialis, starts working within 30-60 minutes. It will only work when you're sexually aroused.

    How long do the effects last?

    • Cialis: Lasts up to 36 hours, making it one of the longest lasting ED treatments.
    • Cialis Daily: Works continuously.
    • Cialis Together: Lasts up to 36 hours.

    How effective is Cialis for men?

    Clinical studies show Cialis is over 80% effective in helping men achieve satisfactory erections. 

    To get the best results, you'll want to take Cialis at least 30 minutes before sex, as outlined in the patient information leaflet.

    Cialis works by supporting your body's natural response when you're turned on. The medication won't create desire or automatically give you an erection. You and your partner will still need foreplay and to be sexually aroused, just as you would naturally. 

    Who can take Cialis tablets?

    Most men aged 18 and over can take Cialis for erectile dysfunction. The different versions suit different lifestyles and needs:

    • Cialis: Ideal for men who have sex less regularly or whose erectile dysfunction is occasional.
    • Cialis Daily: Suited to men who have sex at least twice a week. Also helpful for those in long-term relationships who’d like to be able to have spontaneous sex. particularly helpful for those in long-term relationships who’d like to be able to have spontaneous sex.
    • Cialis Together: Available for men aged 18 and over who want an over-the-counter option.

    Cialis isn't suitable for everyone. Following the advice in the patient information leaflet (and guide from the NHS) it's important to tell your doctor or our clinicians if you:

    • Have ever had an allergic reaction to Cialis or any other medicine.
    • Are taking nitrates for chest pain or heart problems.
    • Have serious heart disease or recently had a heart attack or stroke.
    • Have low blood pressure or uncontrolled high blood pressure.
    • Have ever lost your vision due to reduced blood flow to the eye.
    • Are taking riociguat.
    • Have sickle cell anaemia (an abnormality of red blood cells).
    • Have leukaemia (cancer of blood cells).
    • Have multiple myeloma (cancer of bone marrow).
    • Have Peyronie's disease (curved penis) or a similar problem with your penis.
    • Have a liver or kidney condition.
    • Have a heart condition. Your doctor will advise you whether your heart can take the additional strain of having sex.

    Tadalafil (Cialis) is also sometimes used by doctors, in different dosages and formulations, to treat the symptoms of an enlarged prostate and pulmonary hypertension. 

    How to take Cialis tablets

    Take one Cialis tablet at least 30 minutes before sexual activity and swallow the tablet whole with water. 

    You can take it with or without food, but avoid grapefruit juice as this may affect how well Cialis works.

    Cialis remains effective for up to 36 hours after taking a tablet. This doesn't mean you'll have a continuous erection for that amount of time though. Instead, you'll be able to achieve erections during this 36-hour window when you're sexually aroused.

    You shouldn’t take more than one tablet in a 24-hour period.

    Find out more about how long Cialis takes to work here.

    Can I take Cialis daily?

    Regular Cialis (10mg and 20mg tablets) isn't meant for daily use. These doses are designed to be taken as needed before sexual activity, not every day.

    The alternative, Cialis Daily, comes in lower doses (2.5mg and 5mg) and is specifically designed for everyday use. This gives you the freedom to be spontaneous without having to plan ahead.

    Are Cialis and Cialis Daily interchangeable?

    No, these medicines aren’t interchangeable. That’s because Cialis and Cialis Daily work in different ways and are designed for different needs:

    Cialis (10mg/20mg) is taken as needed, at least 30 minutes before sexual activity, and lasts up to 36 hours.

    Cialis Daily (2.5mg/5mg) is taken once every day at the same time, regardless of when you plan to have sex, and is for patients that anticipate more regular sex (i.e. at least twice weekly).

    As there are two treatment options and they work differently in your body, it's important to speak to your doctor about which option is right for you and your lifestyle. We’ll also help you decide during a short and confidential online consultation.

    Cialis dosages

    Cialis

    • Available in 10mg and 20mg tablets
    • Comes in packs of 4, 8 or 12 tablets
    • The standard dose is 10mg

    Our clinicians will make sure you're on the right dose for your needs. We also recommend giving any ED treatment eight attempts before you consider a dose change or alternative option.

    If 10mg isn't giving you the results you're looking for, you may be advised to try 20mg depending on how you're responding to the treatment.

    Cialis Daily

    • Available in 2.5mg and 5mg tablets
    • Comes in packs of 28 tablets (one for each day of the month)
    • Standard dose is 2.5mg

    Depending on factors like your age, overall health, and how severe your ED is, you might be prescribed the higher 5mg dose. Unlike regular Cialis though, the dosage doesn't affect how quickly Cialis Daily works or how long it stays effective.

    It’s also worth knowing that higher doses of any medication typically come with a greater chance of you experiencing side effects.

    Cialis side effects

    Although Cialis can cause side effects, many men don't experience any. If you do, they're usually mild and typically last only a few hours after taking a dose.

    Common side effects (Up to 1 in 10 people):

    • Headache
    • Back pain
    • Muscle aches
    • Pain in arms and legs
    • Facial flushing
    • Nasal congestion
    • Indigestion  

    These side effects should not last more than a few hours after taking a dose of Cialis.

    Uncommon side effects (Up to 1 in every 100 people):

    • Dizziness
    • Stomach ache
    • Feeling sick
    • Being sick
    • Reflux
    • Blurred vision
    • Eye pain
    • Difficulty breathing
    • Blood in your wee
    • Prolonged erection
    • Pounding heartbeat
    • Fast heart rate
    • High or low blood pressure
    • Nose bleeds
    • Ringing in ears
    • Swollen hands, feet or ankles
    • Tiredness

    The patient information leaflet does list several serious side effects including fainting, seizures, memory loss, hearing problems, severe allergic reactions, and vision changes. But as these may affect up to 1 in 1,000 people, they’re rare.

    Heart attack and stroke have also been reported rarely in men taking Cialis. It’s worth noting though that most of these men had known heart problems before taking this medicine.

    Managing side effects

    You can help reduce some Cialis side effects by:

    • Staying hydrated to avoid headaches
    • Avoiding rich or spicy foods if you are feeling nauseous
    • Keeping cool if you are experiencing hot flushes
    • Taking an antacid if needed for indigestion

    Long-term side effects of taking Cialis

    According to the NHS ‘side effects usually disappear when you stop taking the tablets’ and a 24 month clinical study stated that tadalafil use was ‘safe and ‘well-tolerated;. The side effects apply whether you're taking Cialis occasionally or using it regularly over a longer period.

    If you have been taking Cialis for a long time and have any concerns, you can speak to your GP for a review of your treatment. You can also message us in your account.

    On this page

      Cialis FAQs

      On this page

      Is Cialis stronger than Viagra?

      Cialis and Viagra are both effective ED treatments that work by increasing blood flow to the penis, helping you achieve firmer erections. However, they contain different active ingredients. Cialis contains tadalafil while Viagra contains sildenafil.

      Neither is necessarily ‘stronger’ than the other, but some men may respond better to one medicine over the other. 

      The main difference is how long they last. Cialis, for example, can be effective for up to 36 hours, while Viagra (sildenafil) can be taken up to four hours before sex.

      You can find out more about how Cialis and Viagra are different in our Cialis vs Viagra article.

      Taking Cialis with other medication

      Some medications and recreational substances can interact with Cialis and increase your risk of side effects. So it's important to tell your doctor about any you may be taking. We’ll ask you to do the same during your online consultation. 

      Avoid these completely:

      • Nitrates for chest pain or heart problems.
      • Recreational drugs, particularly 'poppers' or 'room odourisers' that contain organic nitrates or nitric oxide donors such as amyl nitrite. These can cause a dangerous drop in blood pressure when combined with Cialis.
      • Stimulants like MDMA (ecstasy) or cocaine.
      • Hallucinogens like LSD.
      • Novel psychoactive substances (formerly known as legal highs) like mephedrone.
      • Riociguat (used for pulmonary hypertension).

      Use with caution:

      • Alpha-blockers for high blood pressure or prostate problems.
      • Other blood pressure medications.
      • Some antifungal medicines like ketoconazole.
      • Certain antibiotics like erythromycin.
      • HIV/AIDS medications.

      Additional note for Cialis Daily: 

      If you’re taking alpha blockers (such as doxazosin or tamsulosin), nicorandil, or nitrates such as GTN spray or isosorbide mononitrate tablets to treat angina, Cialis Daily won’t be suitable for you.

      Can I drink alcohol while taking Cialis?

      Having a beer or glass of wine is fine and unlikely to affect how Cialis works. But the key is moderation. The patient information leaflet makes it clear that heavy drinking can work against you by:

      • Making it harder to get an erection in the first place.
      • Increasing your chances of headaches or dizziness.
      • Affecting your heart rate and blood pressure.

      To get the best results from Cialis, drink sensibly and remember that alcohol itself can interfere with erections. 

      Does Cialis make you last longer in bed?

      It can, but only if you're struggling with sexual endurance because you're having difficulty getting or keeping an erection.

      Many men find that when they can achieve and keep better erections, they naturally feel more confident and in control during sex.

      If you do get erections, but sex doesn’t last as long as you’d like, you may be experiencing premature ejaculation (PE).

      Is Cialis physically addictive?

      There's no mention of physical addiction in the clinically researched patient information leaflet. There is a possibility some men may develop a psychological reliance on Cialis, particularly if they feel they can't perform without it.

      This is different from physical addiction because your body won't become dependent on Cialis or experience withdrawal symptoms if you stop taking it. Instead, it's more about confidence and peace of mind the medicine provides.

      If you have any concerns, or feel you may be becoming too reliant on Cialis, speak to your GP or message us through your account. 

      Can Cialis cause high blood pressure?

      Cialis can affect your blood pressure. The patient information leaflet lists both high and low blood pressure as side effects affecting up to 1 in 100 people. So they are possible, just rare.

      The NHS also advises that tadalafil may not be suitable if you have low blood pressure (hypotension) or uncontrolled high blood pressure (hypertension).

      Cialis can interact dangerously with nitrate medications for chest pain too. That’s why, if you have existing blood pressure issues or take heart medication, you should speak to your GP before starting this medicine. We’ll also ask you about this during your online consultation. 

      Can Cialis stop working?

      Cialis is an effective treatment for erectile dysfunction. But if it doesn't seem to be working, it's usually due to timing, dosage, or arousal levels rather than the medicine losing its effectiveness.

      Bear in mind too, it’s always recommended you try using any ED medicine at least eight times before you look to switch. 

      If you do want to request a different treatment, we can prescribe from a range of different tablets, creams and sprays.  

      If Cialis stops being effective for you, speak to your doctor, or send us a message in your account. We can review your dosage and explore alternative treatments. Or consider whether any underlying health changes might be affecting your response to the medicine.

      Can I buy Cialis online or over-the-counter without a prescription?

      Although Cialis Together is available over the counter at pharmacies, both Cialis and Cialis Daily are prescription-only medicines.

      If you suffer from erectile dysfunction, will need to complete a short online consultation, which will be reviewed by one of our clinicians. That way, we can make sure Cialis or Cialis Daily is the right choice for you and is safe to use. 

      It also gives us the opportunity to recommend other treatments if they might be more appropriate. 

      Alternative ED treatments

      If Cialis doesn't work for you initially, don't worry. As with any treatment for erectile dysfunction, it’s always recommended you use the medicine about eight times before judging its real effectiveness.

      But if you do want to try a different option, either because Cialis isn’t working or you just want a faster-acting medicine, you can request a consultation where a clinician can review suitability for alternatives. 

      As well as the various medicines designed to treat ED, some men find other things like acupuncture, lifestyle changes and talking therapies can help. Of course, it’s safe to use these more holistic alternatives to support your medical treatment. 

      You’ll find lots of useful information about these options in our article, alternative treatments for erectile dysfunction.

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      2. One of our clinicians confirms your suitability and notifies you by email

        About 30 mins (Mon-Sun 9am-5pm)

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