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Spedra - Erectile dysfunction treatment
  • Works in 15mins for most men
  • Lasts up to 4hrs
  • Works for 60-70% of men


One of the faster-acting ED treatments available.

We're registered with the Care Quality Commission

Spedra - Erectile dysfunction treatment

Branded treatment

Pack size
Returning patient? Reorder
  • Works in 15mins for most men
  • Lasts up to 4hrs
  • Works for 60-70% of men

Generic or branded treatments?

Some treatments contain the same active ingredient but are sold under different names. If the active ingredient and the dosage are the same, the treatments will have the same effect and work in the same way. 

Generic Branded
Same active ingredient
Works in the same way
Often less expensive

What is Spedra?

  • Taking Spedra

    Take one tablet 1hr before sex. Never take more than one tablet within 24hrs. Works best on an empty stomach. Alcohol will limit Spedra's effectiveness. Avoid grapefruit juice for 24 hours prior to taking Spedra. Do not combine Spedra with other ED medicines.

  • How does Spedra work?

    Spedra's active ingredient (avanafil) increases blood flow to the penis. It enables a firmer, longer-lasting erection if you are sexually aroused.

    The treatment will not resolve the underlying physical cause of your ED or increase your sexual desire.

  • How long does Spedra last?

    The effects of Spedra can last for up to 4 hours.

  • What are the side effects?

    Side effects may include facial flushing, headache, light headedness, nasal/sinus congestion, indigestion, palpitations (racing heartbeat), and blurred vision. Please always read the patient leaflet.

    For full information on side effects and correct use, see the patient information leaflet.

  • How effective is Spedra?

    Spedra 100mg treats ED in 58% of cases. Most men find it works quicker than other ED treatments. If you have eaten a large meal or drunk more than 1-2 units of alcohol, you may find it takes longer to work or is less effective.

    We advise trying an ED treatment 8 times before giving up, considering a higher dose, or seeking an alternative.

  • Spedra strength and dosage

    The standard dose is 100mg. Depending on your age, height and weight, the cause and the severity of your ED, you may be prescribed a lower dose of 50mg, or a higher one of 200mg. Dosage does not affect how quickly or for how long the treatment works.

    Higher doses come with an increased chance of developing side effects.

  • Drug interactions with Spedra

    If you take alpha-blockers (such as doxazosin or tamsulosin), you should wait at least 6 hours between taking those and taking Spedra. You will be unsuitable for Spedra if you are taking nicorandil or nitrates, such as GTN spray or isosorbide mononitrate tablets to treat angina.

    Recreational drugs react dangerously with Spedra. It is important that you let us know which prescription, over-the-counter medicines and recreational drugs you are taking so that we can prescribe Spedra safely.

  • Alternative ED treatments

    Some men find counselling helpful as a means of exploring and treating psychological causes for ED.

    If Spedra does not work for you, contact us via your Patient Record so that we can discuss your treatment options. View all our ED treatments.

  • Reordering Spedra

    To reorder Spedra, go to your Patient Record and select ‘reorder’. You will be required to fill in the online questionnaire each time you reorder.

LloydsPharmacy Online Doctor

This service operates in the United Kingdom only

LloydsPharmacy Online Doctor

This service operates in the United Kingdom only

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LloydsPharmacy Online Doctor

This service operates in the Republic of Ireland only

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