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Tadalafil - Erectile dysfunction treatment
  • Can be taken with food
  • Works in 30mins, lasts up to 36hrs
  • Works for 80% of men

Tadalafil 10mg tablets (generic Cialis)

Tadalafil - Erectile dysfunction treatment

Generic treatment

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Alternative treatment: Cialis

  • Can be taken with food
  • Works in 30mins, lasts up to 36hrs
  • Works for 80% of men

On this page

    What is Tadalafil?

    On this page
    1. How does Tadalafil work?
    2. How effective is Tadalafil?
    3. Who can take Tadalafil?
    4. How to take Tadalafil
    5. Tadalafil dosage
    6. Tadalafil side effects

    Tadalafil is a treatment for erectile dysfunction (ED), a common condition for men. It is the generic form of the popular ED treatment, Cialis. Tadalafil comes in the form of film-coated tablets. If you are suffering from erectile dysfunction, you can be prescribed tadalafil by our clinicians following an online consultation.

    How does Tadalafil work?

    Tadalafil's active ingredient (tadalafil) increases blood flow to the penis. It enables a firmer, longer-lasting erection if you are sexually aroused.

    The treatment will not resolve the underlying physical cause of your ED or increase your sexual desire.

    How long does it take for Tadalafil to take effect?

    It usually takes 30-60 minutes for Tadalafil to start working. But don’t forget you will only see the effects if you’re sexually aroused.

    How long does Tadalafil last?

    Tadalafil can be effective for up to 36 hours. However, this can be affected by:

    • Lack of sexual stimulation
    • Drinking alcohol
    • Tolerance to dosage

    How effective is Tadalafil?

    Tadalafil treats ED in 80% of cases. If you have drunk more than 1-2 units of alcohol, you may find Tadalafil is less effective. Food does not impact how Tadalafil works.

    We advise trying an ED treatment 8 times before giving up, considering a higher dose, or seeking an alternative.

    Who can take Tadalafil?

    Do not take Tadalafil if you:

    • Are allergic to Tadalafil or any of its ingredients (check section 6 of the Tadalafil patient information leaflet)
    • Are taking any form of nitrate, like amyl nitrate
    • Have had serious heart disease (including a heart attack in the last 90 days)
    • Have had a stroke in the last 6 months
    • Have issues with high or low blood pressure
    • Have ever had loss of vision because of non-arteritic anterior ischemic optic neuropathy (NAION), a conditio described as "stroke of the eye"
    • Are taking riociguat

    Please talk to your GP before taking Tadalafil if you have:

    • Sickle cell anaemia
    • Multiple myeloma
    • Leukaemia
    • Any deformation of your penis
    • A serious liver problem
    • A severe kidney problem

    How to take Tadalafil

    Take one tablet at least 30 minutes before sex. Effects can last for up to 36 hours. Never take more than one tablet within 36 hours. Alcohol will limit Tadalafil's effectiveness. Do not combine Tadalafil with other ED medicines.

    Can Tadalafil pills be split?

    Splitting Tadalafil tablets is not recommended. You should take Tadalafil tablets in the dosage suggested by your clinician or as explained in the patient information leaflet (see above).

    Tadalafil dosage

    The standard dose is 10mg. Depending on your age, height and weight, the cause and the severity of your ED, you may be prescribed a higher dose of 20mg. Dosage does not affect how quickly or for how long the treatment works.

    Higher doses come with an increased chance of developing side effects.

    Our current available doses of Tadalafil are as follows:

    Pack size / Dosage10mg20mg
    4 tablets£25.00£28.00
    8 tablets£38.00£50.00
    16 tablets£62.00£75.00

    There are also monthly subscriptions available which reduce the cost of each dose by 15%:

    Pack size / Dosage10mg20mg
    4 tablets£21.00/month£23.00/month
    8 tablets£32.00/month£42.00/month
    16 tablets£52.00/month£63.00/month

    “Start with a recommended dose from either your GP or one of our consultations. Not all ED treatments will work the first time they are taken – if your treatment has failed to work on eight separate occasions, talk to your GP and they will suggest further next steps.” - Dr Bhavini Shah

    Tadalafil side effects

    Side effects are uncommon, but can include headaches, indigestion, palpitations (racing heartbeat), light headedness, facial flushing, nasal congestion and muscle aches. These side effects should not last more than a few hours after taking a dose of Tadalafil.

    Tadalafil side effects long-term are rare. Heart problems have been reported by some men, however many of these men had heart issues before taking their medication. It’s important to let our clinicians know of any medical conditions or medication during your consultation.

    For full information on side effects and correct use, see the patient information leaflet.

    On this page

      Tadalafil FAQs

      On this page

      Does Tadalafil help with enlarged prostate? 

      Tadalafil is also used by men who have benign prostatic hyperplasia (BPH). Men who have this condition have difficulty weeing, with a decreased flow amongst other symptoms. Tadalafil reduces these symptoms and reduces the need for prostate surgery.  

      Does Tadalafil lower blood pressure?

      Some studies have found that Tadalafil can reduce average blood pressure for patients with uncontrolled hypertension. Tadalafil has been used in the treatment of pulmonary hypertension. Tadalafil used alongside treatment containing nitrates like chest pain medication can cause blood pressure to drop to dangerously low levels. If you take these medications, please avoid Tadalafil and talk to your GP about an alternative ED treatment.

      “Even though Tadalafil can lower blood pressure, using it as ED treatment is not a substitute for maintaining your overall heart health. The NHS offers blood pressure testing as a part of their NHS health check which is offered to adults in England aged 40 to 74 every 5 years. Know the signs of heart problems and talk to your GP about any concerns.” - Dr Bhavini Shah

      Why is Tadalafil known as the 'weekend' pill?

      You might hear or see people referring to Tadalafil as the ‘weekend’ pill. This is because the effects of Tadalafil can last up to 36 hours, giving you help with getting an erection across a 2.5 day period. Taken on a Friday afternoon/evening the medication could take effect for the whole weekend, hence Tadalafil's nickname of the 'weekend' pill. 

      Can I buy Tadalafil online or without a prescription?

      Do you need a prescription to buy Tadalafil?
      Yes, you need a prescription to request and pay for Tadalafil. 

      Can I buy Tadalafil over the counter?
      No, you cannot currently buy Tadalafil over the counter. 

      Can I buy Tadalafil online?
      No, you cannot currently buy Tadalafil over the counter. You need a prescription to request and pay for Tadalafil.

      Some popular ED treatments, like Viagra Connect, are available over the counter. You will need to answer some questions from the pharmacist providing this treatment to check that this treatment is right for you. 

      Drug interactions with Tadalafil

      You will be unsuitable for Tadalafil if you are taking alpha-blockers (such as doxazosin or tamsulosin), nicorandil or nitrates, such as GTN spray or isosorbide mononitrate tablets to treat angina.

      It is important that you let us know which prescription, over-the-counter medicines and recreational drugs you are taking so that we can prescribe Tadalafil safely.

      Alternative treatments to Tadalafil

      If Tadalafil does not work for you, contact us via your Patient Record so that we can discuss your treatment options. If you're unsure about other available erectile dysfunction treatment options we've created the table below:

      NameViagraLevitraSpedraVitaros
      Active ingredientSildenafilVardenafilAvanafilAlprostadil
      How long to take effect30-60 minutesWithin an hour15-30 minutes5-30 minutes
      How long does it last?Up to 5 hoursUp to 5 hoursUp to 4 hoursUp to 2 hours
      EffectivenessWorks for up to 82% of menWorks for up to 87% of menWorks for up to 58% of menWorks for up to 52% of men

      View all our ED treatments.

      Tadalafil vs Cialis: What’s the difference?

      Tadalafil is the generic form of the branded erectile dysfunction treatment Cialis. Both drugs have the same ingredients, effectiveness and side effects – there’s no difference other than the branding and cost.

      Is Tadalafil stronger than Viagra?

      One medication is not ‘stronger’ than the other, they just work differently and over a different period of time to manage ED. Both relax the smooth muscles in the blood vessels supplying the penis, increasing blood flow. The differences between the two are as follows:


      Tadalafil
      Viagra
      Time to act
      From 30 minutes before sexFrom 60 minutes before sex
      Can you eat before using it?
      YesNo
      Unique common side effects
      Back painDizziness
      Available doses
      10mg, 20mg25mg, 50mg, 100mg
      Duration of effects
      Up to 36 hours4 to 6 hours

      Do not take both drugs together as they act the same way. Doing this will not increase the effects of either treatment but may increase likelihood of suffering from side effects.

      You can find out more about Tadalafil vs Viagra in our article.  

      Non-drug alternatives to Tadalafil

      There are a number of options to address erectile dysfunction and impotence that do not involve medical treatment. These include:

      • A healthy diet
      • Lifestyle improvements, like increased exercise
      • Improving communication in the bedroom
      • Physical tools like constriction rings and penis pumps
      • Counselling

      While there may be medical reasons for your ED, it can also be other factors including unrealistic expectations or performance anxiety. Finding the cause of your erectile dysfunction should be able to help you and your GP determine your treatment going forward.

      Reordering Tadalafil

      If you’d like to reorder Tadalafil, you can go to your Patient Record and select ‘reorder’.

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