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Sumatriptan is a very effective treatment for migraines. Doctors recommend that it be used together with paracetamol or aspirin/ibuprofen. When used like this, it is the treatment of choice.

Sumatriptan is an effective treatment for migraine.

Dr Gigi Taguri

Sumatriptan 50mg | from £2.67 per tablet

Sumatriptan 50mg

Sumatriptan 100mg | from £3.17 per tablet

Sumatriptan 100mg

Key Features
  • Fast and effective treatment for migraine
  • We recommend taking this treatment with over the counter pain relief, such as: paracetamol, aspirin or ibuprofen – please discuss your options with a pharmacist. 
Sumatriptan should be used as soon as the headache phase of your migraine begins.
Dr Gigi Taguri

Key Information

The medicine

Sumatriptan 50mg/100mg

Taking Sumatriptan

Take one tablet when the headache phase of your migraine begins. If you suffer from aura, wait until this is over before taking the medication. Taking a tablet with fizzy water will help it get to work faster.

 How it works                                                     

Sumatriptan works by reversing the chemical changes in the brain that cause a migraine.                                                                  

Side effects

Common Sumatriptan side effects include:

  • Feeling drowsy or dizzy
  • Nausea and vomiting
  • Shortness of breath
  • Flushing
  • Pain or tightness in the throat or chest. If this is severe and does not pass quickly, please seek urgent medical help.


Rare, but serious side effects include: altered liver function, seizures, tremors, visual disturbances and severe allergic reactions.

If you feel very unwell, or experience significant side effects, go to your local Accident & Emergency department immediately or call 999.

Taking Sumatriptan

Sumatriptan should be taken with water, or fizzy water, when the headache phase of your migraine begins. If you experience an aura (warning symptoms that a migraine is about to begin) do not take your medication during this phase, as it may mean that it does not work.

If after two hours your migraine is not completely better, or has come back, you can take another tablet. This can be repeated at two hourly intervals. Do not take more than 300mg Sumatriptan in 24 hours.

Do not mix Sumatriptan with another triptan when treating the same migraine attack.

Sumatriptan should not be used on a daily basis, as this may lead to a medication overuse headache

If your headache gets significantly worse, or you develop any unusual symptoms, you should see a doctor urgently.

What other treatments might help me?

Available from your LloydsPharmacy...

The following treatments should be taken together with your migraine treatment for maximum  relief, but before you use them, please speak to the pharmacist to check they are suitable for you.

Pain Relief

  • Paracetamol 500mg 2 tablets up to four times daily
  • Aspirin 300 - 900mg up to 4 times daily, or Ibuprofen 400mg up to 4 times daily

Anti - sickness

Taking an anti-sickness medication will help you feel better, and can also help your migraine treatment to work faster.

  • Buccastem M 3mg up to twice daily - these tablets are designed to work by placing them under your lip. As you don't have to swallow them, they are particularly good if vomiting is one of your migraine symptoms

Available from your doctor...

The following pain relief and anti-sickness medications are only available on prescription. Please speak to your doctor to see if they are suitable for you.

Anti - sickness

  • Metoclopramide 10mg up to three times daily

Combination pain relief and anti-sickness

The following treatments are soluble, which means they are likely to work faster.

  • Migramax (aspirin 900mg plus metoclopramide 10mg)
  • Paramax (paracetamol 500mg plus metoclopramide 5mg)

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