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    Wegovy® (semaglutide) weight loss injections

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    Wegovy® is a weight loss drug which is used to help people with high body mass indexes (BMI) lose weight. Our clinicians will check your BMI, before they prescribe this treatment.  

    Wegovy is a new drug with the active ingredient, semaglutide, that can be used to help people lose weight by around 15% (over 68 weeks).

    What is Wegovy® (semaglutide)?

    Wegovy® is a weight loss drug containing the active ingredient, semaglutide. It’s injected into the body once a week to help you lose weight. Wegovy® is thought to be an effective weight loss drug when used alongside a healthy, reduced-calorie diet and increased exercise.

    The drug has recently been approved in the UK and is available now. It was approved in the USA in 2021.

    How does Wegovy® work?

    Wegovy® essentially works by suppressing the appetite and regulating food intake. The active ingredient, semaglutide, mimics the action of the hormone that’s involved in regulating appetite. This means you feel fuller for longer and less hungry. This can help you to eat less and hopefully lose weight.

    The starting dose is 0.25mg, if you’re tolerating the treatment after 4 weeks you’ll step up in dose. The highest dose 2.4mg, which has seen positive results in 2 year trials.

    Wegovy® works best when it’s taken at the same time as making lifestyle changes (healthier diet and increased exercise). In fact, around 85% of users lost at least 5% of their weight, compared to just 40% losing 5% when no lifestyle changes were made. 

    “Wegovy® is a weekly injection which suppresses your appetite and slows digestion. Combined with a reduced-calorie diet and becoming more physically active, this should help you on your weight-loss journey.” - Dr Bhavini Shah

    How effective is Wegovy® (semaglutide)?

    When Wegovy® is combined with a reduced calorie diet and increased exercise, a 68-week study has shown that:

    • Around 85% of people lost more than 5% of their body weight
    • 66% of people lost more than 10% of their body weight
    • 48% of people lost more than 15% of their body weight
    • 30% of people lost more than 20% of their body weight 

    This compares to just 63.5% of people losing 5% of their weight when taking Saxenda® along with a reduced calorie diet and physical activity counselling. 

    Wegovy 68 week study graph

    Wegovy® vs. other weight loss injections 

    Wegovy® is one of several weight loss injections available via prescription. Other popular treatments include Mounjaro® and Ozempic®. Even though Ozempic® has the same active ingredient as Wegovy®, it can only be prescribed off-book as it is intended to be used for type-2 diabetes. We’ve highlighted the key differences between the injections below:

    Name
    Wegovy®
    Mounjaro®
    Ozempic®
    Active ingredient
    SemaglutideTirzepatideSemaglutide
    Primarily used for
    Weight lossWeight lossBlood sugar regulation for type-2 diabetics
    How to take it
    Weekly injectionWeekly injectionWeekly injection
    How it works
    Reduces / regulates appetite
    Reduces / regulates appetite
    Reduces / regulates appetite
    Effectiveness
    84%96%N/A

    *% of people losing more than 5% of body weight. Ozempic® does not have a value as it has not been tested as a weight loss drug.

    “There are many different options for weight loss. You can compare the different treatments and our clinicians will help to find out what works best for you.” - Dr Bhavini Shah

    Who can use Wegovy®?

    Wegovy® can be used by adults ages 18-75 who have:

    • A BMI of 30 or above
    • A BMI of 27 or above and you have a weight-related health condition such as:
    • Cardiovascular disease
    • Diabetes (As we are an online service, we are unable to prescribe Wegovy to diabetics for patient safety reasons) 
    • High blood pressure
    • PCOS 
    • Sleep apnoea 

    You won’t be able to take Wegovy® if you:  

    • Are over 75
    • Are pregnant or breastfeeding
    • Have liver, kidney or heart failure, an eating disorder or pancreatitis
    • Are taking insulin, sulphonylureas or other weight loss drugs that work in the same way as Wegovy®, e.g. Victoza.  

    Wegovy® Dosage

    Wegovy dosing schedule

    Wegovy® injections come in a variety of doses. Depending on where you are in your Wegovy® journey, you will need to take a different dose.

    The dose is gradually increased to make sure you cope with any potential side effects until you get to a maintenance dose, this process is known as titration. Find out how to know when to increase your dose.

    If all goes to plan and you can tolerate the treatment, the dosing schedule will be as follows:

    Treatment stageWeeks 1-4Weeks 5-8Weeks 9-12Weeks 13-16Weeks 17+
    Dosage
    0.25mg weekly0.5mg weekly1mg weekly1.7mg weekly2.4mg weekly

    How to use Wegovy®

    You inject Wegovy® just once a week into your tummy, thigh or upper arm. Read our article to find out more about how to inject yourself.

    What foods can’t you eat whilst taking Wegovy®?

    Wegovy® works best when it’s taken at the same time as making lifestyle changes (healthier diet and increased exercise). In fact, around 85% of users lost at least 5% of their weight, compared to just 40% losing 5% when no lifestyle changes were made.

    Being on Wegovy® doesn’t forbid you from eating any food (though it won’t get rid of any current allergies or intolerances you already have). However, it’s best to avoid the following foods if you want to eat a reduced calorie diet:

    • Foods high in saturated fats
    • Fried foods
    • Fast food
    • Processed meat
    • Full-fat dairy

    What happens if you miss a dose of Wegovy®?

    If you’ve missed a dose of Wegovy®, check how many days it has been since your last injection.

    If your last Wegovy® injection was 5 days ago or shorter
    Inject Wegovy® as soon as possible. After that, return to your original dose schedule.

    If your last Wegovy® injection was longer than 5 days ago
    Skip your missed dose and do not inject Wegovy® until your next scheduled day. Do not take a double dose of Wegovy®. This will not ‘make up’ for the dose you’ve missed – you’re just increasing the likelihood of suffering from side effects like nausea or vomiting.

    Wegovy® side effects

    Like all medications, some people might feel some side effects from taking Wegovy®. We’ve listed these possible side effects, some common and others not-so-common, below:

    Likelihood
    Serious side effects
    Other side effects
    Common (may affect 1 in 10 people)
    • Complications of diabetic eye disease (diabetic retinopathy)
    • Dizziness
    • Upset stomach or indigestion
    • Reflux or heartburn
    • Gallstones
    • Hair loss
    • Change in taste
    • Change in skin sensation
    Uncommon (may affect up to 1 in 100 people)
    • Inflamed pancreas
    • Kidney or bladder stones
    • Fast heartbeat
    • Increase of pancreatic enzymes shown in blood tests
    • Delay in emptying the stomach
    • Low blood sugar in patients without diabetes
    • Jaundice
    Rare (may affect up to 1 in 1000 people)
    • Angioedema - a swelling under the skin often caused by something you're allergic to
    • Anaphylactic reaction - a sever allergic reaction which will need urgent medical attention
    • Hip fractures
    N/A
    Not known
    • Bowel obstruction

    N/A

    If you start experiencing any side effects, please talk to your GP. For more information about Wegovy®, read the patient information leaflet or our guide to Wegovy® side effects.

    How Wegovy® works

    1. Suppresses appetite

      Wegovy® makes you feel less hungry

    2. Helps you feel fuller

      Wegovy® slows down digestion

    3. Combines with lifestyle changes

      Lose more weight with diet and exercise

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      About Wegovy®

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      Is Wegovy® addictive?

      There is currently no evidence to suggest that Wegovy® is addictive. However, any medication can be misused. If you feel that your relationship with a treatment is becoming unhealthy, please talk to your GP.

      Does Wegovy® burn fat?

      Wegovy® does not work by burning fat. Wegovy® mimics the hormone GLP-1 to regulate appetite. This makes you less hungry, so helps you to eat less.

      The best way for you to burn fat is to exercise. It’s important to stay active and eat healthily to help with fat loss.

      How long does Wegovy® take to work?

      Wegovy® has been shown to be an effective weight loss treatment, when used alongside a reduced-calorie diet and increased physical activity.  

      In clinical trials (Step 1 and Step 4), around 85% of people lost more than 5% of their body weight when using Wegovy and following a reduced-calorie diet and increased exercise plan:  

      • Around 85% people lost at least 5% of their starting body weight after 6 months 
      • Around 66% people lost more than 15% of their starting body weight after one year 

      Wegovy® price

      If you’re considering Wegovy® as the next step in your weight loss journey, you may be wondering ‘how much does Wegovy® cost’?
      As mentioned at the top of the page, Wegovy®’s price at LloydsPharmacy Online Doctor starts from £37.25/dose for 0.25mg pens (sold in packs of four). Aside from the jump between 0.5mg and 1mg, the price increases alongside the dose. Find a breakdown of Wegovy® price per dose below:

      • 0.25mg - £37.25
      • 0.5mg - £44.75
      • 1mg - £44.75
      • 1.7mg - £56
      • 2.4mg - £67.25

      Wegovy® and heart health

      Wegovy® is the first weight loss medication that can be prescribed to reduce the risk of heart attacks and strokes in overweight and obese adults with a BMI higher or equal to 27.  Find out more about Wegovy® and heart health

      Can I take Wegovy® if I’m on the contraceptive pill?

      You can take Wegovy® if you’re on the contraceptive pill. There isn’t any evidence at the moment that suggests Wegovy® affects contraception.

      Does Wegovy® need to be kept in the fridge?

      Any Wegovy® pens that haven’t been opened should be kept in the fridge.

      How to store and dispose of Wegovy® pens

      Storing your Wegovy® pens – cold storage during delivery

      • We use packaging that keeps your treatment at the right temperature (2-8°C) for up to 36 hours during transit.
      • If cold storage is disrupted during the delivery process, the medication will be able to be used for up to 46 days. 
      • Once you have received your medication it is important you keep it stored in the fridge.

      How to store your Wegovy® pens

      • Any Wegovy® pens that haven’t been opened should be kept in the fridge.
      • During use you can keep the pens for 42 days in the fridge or room temperature (below 30°C).

      How to throw away your Wegovy® pens

      • Pens need to be disposed of in the sharps bin you’re given when you start your treatment.
      • When you're prescribed Wegovy® you’ll need to check your local council’s website to find out how to get rid of the sharps bin and its contents. 

      Do I need to be in a calorie deficit on Wegovy®?

      It’s recommended that you eat a reduced calorie diet and increase physical activity while on Wegovy® for maximum effectiveness.

      To operate on a calorie deficit, you need to burn more calories a day than you’re taking in. Eat healthily, cutting sugar and fat while increasing fruits and vegetables, lean proteins and whole grains.

      Can you take Wegovy® for weight loss without diabetes?

      Yes - you do not need diabetes to be prescribed Wegovy®. Our clinicians will discuss any health conditions you have as a part of our online consultation, before any prescription is issued. This is done so that any treatment is suitable – and safe – for you.

      Are Ozempic® and Wegovy® the same?

      While Ozempic® and Wegovy® contain the same active ingredient, semaglutide, they are not the same.

      What are the differences between Wegovy® and Ozempic®?
      The main differences between Wegovy® and Ozempic® are:

      • The amount of semaglutide in each medication
      • Wegovy® is licensed for weight loss whereas Ozempic® is only licensed to treat type-2 diabetes. This means that any weight loss prescription for it would have to be off-book

      Learn more about Wegovy® and Ozempic®.

      Can I switch from Wegovy® to Mounjaro®?

      Yes – it’s possible to switch from one weight loss injection to the other. Do not take both at the same time as this can result in serious side effects.

      If you’re considering switching from Wegovy® to Mounjaro® (or vice versa), please talk to your GP. Consider:

      • How much weight you've lost on your current treatment
      • If you're experiencing any side effects

      If you want to find out more details on changing your treatment, read our guide on Wegovy® vs Mounjaro®.

      What is the difference between Wegovy® and Saxenda®?

      Although made by the same manufacturer Wegovy® and Saxenda® are different. The main difference is how often you need to use them. You would need to inject Wegovy® once a week but Saxenda® needs to be injected daily.

      They also contain different active ingredients. Wegovy® contains Semaglutide while Saxenda® contains Liraglutide. Yet, these work in similar ways to suppress your appetite to help you to lose weight.     

      Alternative weight loss treatments

      There are weight loss treatments available in the UK, other than Wegovy®. We recommend that you speak to a clinician to find out what is right for you.

      Other weight loss treatments include:

      The NHS has helpful weight loss diets and exercise routines which can support you on your weight loss journey alongside a medicated treatment.

      You may have heard of Ozempic®. Although it contains the same active ingredient as Wegovy® it’s licensed for adults who have type 2 diabetes. Find out the difference between Ozempic® and Wegovy®.   

      Important Information about Wegovy® UK delivery

      When is Wegovy® dispatched?

      • Wegovy® will be dispatched Sunday - Friday only for next day delivery.
      • Orders approved before 5pm will be dispatched via next day delivery.
      • Orders approved after 5pm will be delivered in two working days.
      • Orders approved after 5pm on Friday up to midday Sunday will be dispatched for delivery on Monday.
      • Orders approved from midday Sunday to 5pm Monday will be delivered on Tuesday.

      Delivery address information

      • Wegovy® must be delivered to your home address to ensure safe storage as soon as possible.
      • Please follow the tracking information provided by Evri to make sure you are available for delivery.
      • LloydsPharmacy Online Doctor cannot take any responsibility for lost or stolen parcels once delivery has taken place, and no refunds will be issued.
      • Please do not use a pharmacy address. It is likely your delivery will be rejected or disposed of. No refunds will be issued if this happens.
      • Please do not divert your order to a ParcelShop. This extends the delivery time and means your medication isn’t kept at the right temperature. No refunds or resends will be issued if your order is diverted from the original delivery address. 

      Northern Ireland

      • If you live in Northern Ireland, it’s important you know that Wegovy® will be prescribed for you off label. This means the manufacturers haven’t licenced the use of Wegovy® in Northern Ireland yet.
      • We will still ensure Wegovy® is safe for you to take according to the guidelines we use in Great Britain.

      Requesting Wegovy® (semaglutide) from LloydsPharmacy Online Doctor

      If you’d like to request Wegovy® for weight loss, please complete our weight loss consultation. The consultation will ask you a series of questions to assess if the treatment is right for you.

      If it’s your first-time ordering Wegovy® from us, you’ll need to upload a video showing your ID and weight, so we can verify your identity and BMI. If you’re prescribed, you can have your treatment delivered the next day.

      How will Online Doctor support you whilst taking Wegovy® (semaglutide)?

      If you’re taking Wegovy® (semaglutide) injections, our clinicians will support you through your journey in a variety of different ways:

      1. As part of your ongoing support from our clinical team, we’ll send you a follow up questionnaire after you’ve been taking the treatment for around one week, to see how you’re getting on.
      2. We have a range of healthy lifestyle advice and wellbeing resources to support you on your weight loss journey. The included nutritional assessment offers information on national dietary guidelines and main food groups to help you improve your overall health.
      3. We’ll remind you when it’s time to reorder, so you don’t miss out on treatment.   

      At certain intervals you’ll be asked to update our clinicians on your weight, to make sure the treatment is still suitable.

      If you have any questions or queries you can send our team a message in your Patient Record.  

      Available treatments on LloydsPharmacy Online Doctor

      Name Mounjaro® Wegovy® Saxenda® Orlistat/Xenical
      Active ingredient Tirzepatide Semaglutide Liraglutide Orlistat
      How to take it Weekly injection Weekly injection Daily injection Up to three daily tablets
      How it works Reduces/regulates appetite Reduces/regulates appetite Reduces/regulates appetite Reduces fat absorption
      Effectiveness* 96% 84% 60% 45%
      *% of people losing more than 5% of body weight.

      What our patients say

      How our online weight loss service works

      1. Complete our simple, confidential online consultation

        5 mins

      2. One of our clinicians confirms your suitability

        Mon - Fri 9am - 5pm

      3. Discreet delivery to your door

        Next day delivery

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