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Spedra is used to treat erectile dysfunction by increasing the flow of blood to the penis. It is more targeted than other ED treatments and can be quicker to take effect. Spedra is available by prescription from our online clinic.

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    Avanafil 50mg | from £5.06 per tablet

    Spedra 50mg - Erectile Dysfunction Treatment

    Avanafil 100mg | from £6.19 per tablet

    Spedra 100mg - Erectile Dysfunction Treatment

    Avanafil 200mg | from £8.69 per tablet

    Spedra 200mg - Erectile Dysfunction Treatment

    Key Features
    • Takes effect within 15 minutes for some men
    • Remains effective for around four to five hours
    • Gives a firmer and longer-lasting erection when aroused
    Spedra can work faster than Viagra, in fact some men feel the effect within 15 minutes.
    Dr Clyde Mackey

    Key Information

    The medicine

    Spedra (avanafil)

    Taking Spedra

    Take one tablet thirty minutes before sex. Spedra can be taken with or without food; if taken with food, it may take longer to work. Positive effects can last for four hours or longer.

    You should not take Spedra more than once a day. Grapefruit juice should be avoided within 24 hours prior to taking Spedra. Drinking alcohol at the same time as taking Spedra may increase your heart rate and lower your blood pressure. It may also decrease your ability to get an erection.

    How it works

    It works by increasing blood flow into the erectile tissue of the penis. Spedra does not have an effect on your sexual desire, but will improve your erection if you are sexually aroused.


    The majority of men will notice a firmer and longer-lasting erection. If you find that the treatment does not work, ask our doctors whether it would be appropriate to increase the dose or to try a different medicine.

    If Spedra doesn’t work for you first time round, it could nevertheless be more effective next time. Indeed, doctors advise trying all erectile dysfunction medicines eight times before giving up.

    Side effects

    As Spedra is a new drug, there is limited experience in its use. Drug trials are very reassuring, but we may not yet be aware of all the rare side effects. Common side effects include facial flushing, headache, light headedness, nasal/sinus congestion, indigestion, a pounding heartbeat and blurred vision. Please read the manufacturers leaflet for all side effects.

    Nitrates and Spedra

    Our doctors will not be able to prescribe Spedra if you are taking nicorandil or nitrates, such as GTN spray or isosorbide mononitrate tablets to treat angina.

    Alpha-blockers and Spedra

    If you are taking alpha-blockers, our doctors will advise that you leave at least six hours between taking your alpha-blocker and taking Spedra.

    About Spedra

    How quickly does Spedra take effect?

    Spedra is a targeted medicine and should take effect within 15 to 30 minutes for most men, making it one of the fastest-acting ED medicines on the market.

    Does Spedra treat the underlying causes of erectile dysfunction?

    No. Unfortunately, ED medicines (including Spedra) do not treat the underlying causes of erectile dysfunction on a physical level. They can, however, help patients psychologically, giving a boost in confidence that allows them to get over anxiety-induced erectile dysfunction.

    In many men, erectile dysfunction is the first sign of some medical problems, such as high blood pressure or diabetes. It’s important, especially in men over the age of 40, to have physical examinations and blood tests to assess the possibility of other underlying health conditions. Treatment of these conditions is important for your overall health, as well as your sexual health.

    Alternative Treatments

    Other Medicines

    Key InformationFaster and longest actingSame active ingredient as ViagraRecommended for diabeticsBest known treatment


    Psychological Therapy

    Some men find counselling helpful as a means of exploring psychological causes for ED. If you wish to try counselling then some sexual health clinics (also known as GUM clinics) offer this service. 

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