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    Lymecycline and Epiduo gel

    On this page

    How do take Lymecycline and apply Epiduo gel?

    Take Lymecycline once a day with water, preferably in the morning.

    Epiduo gel should be applied in a thin layer to the affected area each evening before going to bed.

    Epiduo gel is likely to bleach any fabric it comes into contact with, as well as the hair so be sure to wash your hands thoroughly after use.

    How does this combination of acne treatments work?

    As Lymecycline is an antibiotic it works to kill the bacteria that cause acne in the first place.

    Epiduo gel contains two active ingredients, Adapalene and Benzoyl Peroxide.

    These work together to interrupt the skin processes that cause acne, softening and peeling the skin as well as working as an antimicrobial agent.

    Will Lymecycline and Epiduo gel be an effective treatment?

    This combination package of acne treatments is likely to be most effective for those people who experience mild to moderate acne that is characterised by larger spots and lumps (nodules/cysts).

    It could take 4 weeks before you start to see an impact on your skin.

    Will I experience any side effects with this treatment?

    Lymecycline can cause, can cause side effects including nausea, diarrhoea, headaches and tummy pain. 

    Epiduo gel may cause redness, dryness, skin peeling and a mild burning sensation.

    For full information on side effects and correct use, see the Lymecycline and Epiduo gel patient information leaflets.

    Can I take Lymecycline or apply Epiduo gel during pregnancy or breastfeeding?

    You should avoid using either medication whilst pregnant or breastfeeding.

    Will Lymecycline or Epiduo gel interact with other medications?

    Lymecycline can sometimes interfere with the effectiveness of other prescription and non-prescription medications, so make sure you let us know if you are taking any medications when requesting acne treatment.

    During the course of treatment do not use any products that contain Benzoyl Peroxide and/or retinoids.

    Alternative acne treatments

    Some people may use a topical gel or cream on its own to treat their acne, and some women who suffer from hormonal acne may be prescribed the contraceptive pill Co-cyprindiol (a common branded version being Dianette or Clairette).

    Reordering treatment

    We will contact you through your Patient Record 6 weeks from your order to see how you are getting on with the medication. We may ask for some photos at this time as well to assess the response to treatment. It will also be an opportunity for you to give us feedback on your acne. Go to your Patient Record and select ‘reorder’. You will be required to fill in the online questionnaire each time you reorder.

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    How our service works

    1. Complete our simple, confidential online consultation

      5 mins

    2. One of our clinicians confirms your suitability and notifies you by email

      About 30 mins (Mon-Sun 9am-5pm)

    3. Choose delivery or collection

      Next day delivery

      Collect in your local ParcelShop​​​​​​​

    What our patients say

    Meet our clinical team

    Based in our London office, our doctors and independent pharmacists have years of experience caring for patients in NHS hospitals, GP surgeries or in community pharmacies. Any one of the team may provide you with advice, your prescription or aftercare via private message.

    Meet the whole team
    • Dr Kieran Seyan  - Meet the clinical team at LloydsPharmacy Online Doctor

      Dr Kieran Seyan

      GMC: 6104204

    • Dr Gigi Taguri  - Meet the clinical team at LloydsPharmacy Online Doctor

      Dr Gigi Taguri

      GMC: 6129350

    • Dr Mitra Dutt- Meet the clinical team at LloydsPharmacy Online Doctor

      Dr Mitra Dutt

      GMC: 6077868

    • Dr Neel Patel

      Dr Neel Patel

      GMC: 7085151

    Meet the whole team

    Delivery & collection information

    • Standard delivery


      Delivered within 2-3 working days.

    • Next-day delivery


      Orders approved before 5pm Monday-Friday will arrive within 1-2 working days. Orders approved between 5pm Friday and 12pm Sunday will usually arrive on Monday or Tuesday.

    • Standard ParcelShop collection


      Collect from 7000+ convenient ParcelShops in 2-3 working days.

    • Next day ParcelShop collection


      Collect next day from 7000+ convenient ParcelShop locations, if approved before 5pm Monday-Friday. Saturday and Sunday orders, collect Monday if approved before 12pm Sunday or Tuesday if ordered after 12pm. 

    • London same-day collection


      Order before 5pm Monday-Friday to collect in pharmacy the same day. Subject to the availability of your treatment in your selected London pharmacy.

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        LloydsPharmacy Online Doctor

        This service operates in the United Kingdom only

        LloydsPharmacy Online Doctor

        This service operates in the United Kingdom only

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        LloydsPharmacy Online Doctor

        This service operates in the Republic of Ireland only

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