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    Lymecycline and Adapalene gel

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    How do I take Lymecycline and apply Adapalene gel?

    Lymecycline should be taken once a day (preferably in the morning) with water.

    Adapalene gel (generic Differin) should be applied in a thin layer to the affected area each evening.

    How will Lymecycline and Adapalene gel work?

    Lymecycline is an antibiotic and therefore works to kill the bacteria that cause acne. Adapalene is a retinoid that works to remove whiteheads and blackheads (comedones), prevent the formation of further comedones by unblocking pores clogged with excess sebum and reduce inflammation.

    Will this acne treatment be effective?

    The double action of this combination means that it both deals with the cause of acne (the bacteria) as well as the appearance of acne at the affected area. 

    It is worth noting this treatment combination is most suited to those experiencing comedones, nodules or cysts as part of their acne. It could be 6 weeks before you start to see a change in your acne.

    Are there any side effects to Lymecycline or Adapalene gel?

    Lymecycline, like a lot of medications, may cause side effects in some people. This side effects include nausea, stomach pain, diarrhoea and headaches.

    Adapalene gel may cause some redness, dryness, irritation or a burning sensation to the affected area.

    For full information on side effects and correct use, see the Lymecycline and Adapalene gel patient information leaflets.

    Should I use Lymecycline or Adapalene gel during pregnancy or breastfeeding?

    Neither Lymecycline or Adapalene gel should be used if you are pregnant, think you may be pregnant or you are breastfeeding.

    Will either medication interact with other medicines?

    It is important you let us know about any medications you may be taking when you go through this consultation as Lymecycline may interfere with their effectiveness.

    When using Adapalene gel you should avoid any products that contain tretinoin, isotretinoin or tazarotene as these may increase irritation and dryness.

    Alternative acne treatments

    Some people may use a topical gel or cream on its own to treat their acne, and some women who suffer from hormonal acne may be prescribed the contraceptive pill Co-cyprindiol (a common branded version being Dianette).

    Reordering treatment

    We will contact you through your Patient Record 6 weeks from your order to see how you are getting on with the medication. We may ask for some photos at this time as well to assess the response to treatment. It will also be an opportunity for you to give us feedback on your acne. Go to your Patient Record and select ‘reorder’. You will be required to fill in the online questionnaire each time you reorder.

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    How our service works

    1. Complete our simple, confidential online consultation

      5 mins

    2. One of our clinicians confirms your suitability and notifies you by email

      About 30 mins (Mon-Sun 9am-5pm)

    3. Choose delivery or collection

      Next day delivery

      Collect in your local ParcelShop​​​​​​​

    What our patients say

    Meet our clinical team

    Based in our London office, our doctors and independent pharmacists have years of experience caring for patients in NHS hospitals, GP surgeries or in community pharmacies. Any one of the team may provide you with advice, your prescription or aftercare via private message.

    Meet the whole team
    • Dr Kieran Seyan  - Meet the clinical team at LloydsPharmacy Online Doctor

      Dr Kieran Seyan

      GMC: 6104204

    • Dr Gigi Taguri  - Meet the clinical team at LloydsPharmacy Online Doctor

      Dr Gigi Taguri

      GMC: 6129350

    • Dr Mitra Dutt- Meet the clinical team at LloydsPharmacy Online Doctor

      Dr Mitra Dutt

      GMC: 6077868

    • Dr Neel Patel

      Dr Neel Patel

      GMC: 7085151

    Meet the whole team

    Delivery & collection information

    • Standard delivery


      Delivered within 2-3 working days.

    • Next-day delivery


      Orders approved before 5pm Monday-Friday will arrive within 1-2 working days. Orders approved between 5pm Friday and 12pm Sunday will usually arrive on Monday or Tuesday.

    • Standard ParcelShop collection


      Collect from 7000+ convenient ParcelShops in 2-3 working days.

    • Next day ParcelShop collection


      Collect next day from 7000+ convenient ParcelShop locations, if approved before 5pm Monday-Friday. Saturday and Sunday orders, collect Monday if approved before 12pm Sunday or Tuesday if ordered after 12pm. 

    • London same-day collection


      Order before 5pm Monday-Friday to collect in pharmacy the same day. Subject to the availability of your treatment in your selected London pharmacy.

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        LloydsPharmacy Online Doctor

        This service operates in the United Kingdom only

        LloydsPharmacy Online Doctor

        This service operates in the United Kingdom only

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        LloydsPharmacy Online Doctor

        This service operates in the Republic of Ireland only

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