Doxycycline and Epiduo gel

Doxycycline must be taken with lots of water, preferably with a meal and always while you are sat or stood up.

Epiduo gel should be applied in a thin layer to the affected area once a day. Apply it after washing and drying the face and prior to going to bed. Make sure you wash your hands thoroughly after applying as it will bleach fabric, towels and hair.

Doxycycline is an antibiotic that works to kill the bacteria that cause acne. Epiduo gel contains both Adapalene and Benzoyl Peroxide, meaning it works in two different veins.  

Adapalene is a retinoid and works to breakdown blackheads and whiteheads, reduce inflammation and prevent the formation of microcomedones (the precursor to acne lesions). Benzoyl Peroxide softens and peels the outer layer of skin, as well as killing acne-causing bacteria.

For people who experience pustules (small red bumps filled with pus), nodules and cysts (larger lumps) this combination of medications is likely to be effective. Breaking down skin processes that produce acne, coupled with its antibacterial action makes it a rounded treatment for those experiencing mild to moderate acne.

Both these medications are likely to make the skin more sensitive to the sun, so it is important you protect yourself from sunlight and use a suitable sun cream.

Doxycycline causes side effects in some people including nausea, tummy pain, shortness of breath, racing heartbeat and dizziness when standing up. Epiduo can also cause side effects, the most common being a mild burning sensation, redness, dryness and peeling of the affected area.

For full information on side effects and correct use, see the Doxycycline and Epiduo patient information leaflets.