Co-cyprindiol and Adapalene Gel

Co-cyprindiol (often known as Dianette or Clairette) is to be started by women on the first day of their period, then taken for 21 consecutive days, followed by a 7-day break. Co-cyprindiol will also act as a contraceptive as well as treat your acne, provided you take it correctly. You should use the Adapalene gel (generic Differin) alongside Co-cyprindiol, daily applying a thin layer of the acne treatment to the affected area.  

To get the most of your acne treatment, you should take the pill at the same time each day and ensure you are applying Adapalene gel every night.

The combination of contraceptive pill Co-cyprindiol and topical Adapalene gel deals with acne from two different angles.

Co-cyprindiol contains cyproterone with ethinylestradiol which helps to block the hormones that cause acne, therefore preventing acne from forming.

Adapalene gel is a retinoid and gets to work on the redness and inflammation caused by acne. It unblocks pores and reduces blackheads and whiteheads.

The two-pronged action of this combination treatment means that it can be very effective in treating acne.

This combination is particularly effective for those who experience comedogenic acne (blackheads and whiteheads) and small red, sore spots called papules. It can take 4 to 12 weeks before you start to see any change to your skin.

Some women taking Co-cyprindiol may experience nausea, changes to body weight, headaches, changes to mood and breast tenderness. Adapalene gel can cause dry skin, irritation to the affected area, burning sensation and redness.

For full information on side effects and correct use, see the Co-cyprindiol and Adapalene gel patient information leaflets.