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Malarone is a well-known and effective medicine used to prevent and treat malaria. It should be taken every day if you are travelling to a malaria risk area (visit Fit for Travel to find out if your destination is affected). Ordering Malarone online can save you the trouble of going to see a doctor face to face.

Atovaquone 250mg / Proguanil hydrochloride 100mg

Malarone Malaria Tablet 250mg

Atovaquone 250mg / Proguanil hydrochloride 100mg

Malarone Malaria Tablet 250mg

Key Features
  • 90-100% effective when used in conjunction with other measures to prevent mosquito bites
  • Side effects are usually mild 
  • For a 7 day trip, 16 tablets will be prescribed (to cover the 2 days before you leave, the duration of your stay, and the 7 days after you return)
Malarone has been proven to be effective in preventing malaria when used in conjunction with other measures.
Dr Gigi Taguri

Key Information

The medicine

Malarone is a medicine that helps prevent malaria. It contains two active ingredients - atovaquone and proguanil hydrochloride.

How it works

Malaria is spread by the bite of an infected mosquito. The mosquito passes the malaria into your bloodstream, infecting you. Malarone prevents malaria by killing the parasites that cause the disease.

How quickly it works

You'll be protected 1-2 days after starting your course – so you need to start taking the medicine before you leave to ensure you'll be protected by the time you arrive at your destination. You will then need to continue every day until seven days after leaving the malaria area.


For Malarone to be fully effective it should be taken once a day and according to the instructions to give you maximum protection. You should also use insect repellent.

Side effects

Side effects from Malarone are uncommon and usually mild, but the medicine can sometimes cause stomach pain, dizziness, headache, nausea, diarrhoea, coughing or mouth ulcers. You may experience vivid dreams.

Taking Malarone

You should take Malarone at the same time each day with food or a milky drink.

You will need to start taking the tablets daily, 1-2 days before visiting a malaria risk area, and keep taking the tablets every day for a week after you leave. As well as taking Malarone, you should use DEET and take other measures to prevent being bitten by a mosquito in the first place.

Before you order please be aware that:

  • we only offer this service to patients over 18
  • each traveller needs to fill out their own assessment form
  • we can't prescribe tablets for your friends or family unless they fill out their own assessment form.

Alternative Treatments

Not all malaria prevention drugs are suitable for all parts of the world. You should check which tablets are recommended for your destination.

The other malaria tablets which we offer at LloydsPharmacy Online Doctor are:

As well as taking malaria tablets, you must take other measures to protect yourself against malaria when in a malaria area. As malaria is spread by mosquitoes, these involve avoiding being bitten by a mosquito in the first place. You should:

  • use insect repellent such as DEET
  • sleep under a mosquito net, preferably treated with insecticide
  • wear long-sleeved shirts and trousers in the evening

Read our article on avoiding mosquito bites for more information.

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